Mayo Clinic researchers have discovered that reducing calories in mice with PKD can prevent, improve, and reverse the disease. They saw a decrease in kidney inflammation, cell injury, and fibrosis. Restricting calories by 40% produced the most dramatic results, “almost completely” preventing and reversing CKD, but even a 10% reduction improved the disease. The researchers believe that a moderate reduction of calories in the 10% range in humans may be enough to delay PKD progression. Further studies will be needed to find out whether this is true and to pinpoint the type of calories (from fats, sugars, etc.) to be cut.
Food Restriction Helps Mice with Kidney Disease, Medical Xpress, November 24, 2015