Anne Riquier-Brison, Ph.D. is the recipient of the John McKay Fellowship in Renal Research at USC for 2010. Dr Riquier-Brison received her Ph.D. in Systems Biology and Disease at the USC Keck School of Medicine. Working under the mentorship of Dr. Alicia A. McDonough, she developed a keen interest in renal disease and the causes of hypertension. During her graduate training, Dr. Riquier-Brison received an NIH-sponsored pre-doctoral training fellowship to study the regulation of sodium transporters in the renal proximal tubule during hypertension. Her Ph.D. research focused on how renal sodium transport was regulated by changes in blood pressure. Her work garnered national recognition, receiving both the Water and Electrolyte Homeostasis Section pre-doctoral trainee award and Cell and Molecular Physiology Section Student Award, both from the American Physiological Society.
After receiving the Ph.D. degree in 2009, Dr. Riquier-Brison decided to stay at USC as a post-doctoral fellow to pursue her training in renal research with Dr. Janos Peti-Peterdi. In Dr. Peti-Peterdi’s laboratory, she focuses her efforts on determining the importance of a novel pathway likely involved in the development of hypertension. The long-term goal of these studies is to provide clinically important information that will be used to develop new drugs and therapeutic and diagnostic approaches for the more effective treatment of hypertension, cardiovascular, and kidney diseases.
Besides numerous presentations at national and international scientific meetings, Dr. Riquier-Brison has published four papers during her graduate training:
- Anne D. M.Riquier-Brison, Patrick K. K. Leong, Kaarina Pihakaski-Maunsbach, and Alicia A. McDonough. Angiotensin II stimulates trafficking of NHE3, NaPi2 and associated proteins into the proximal tubule microvilli. Am J Physiol Renal Physiol, Jan 2010; 298:F177 – F186.
- Anne D. M. Riquier, Donna H. Lee, and Alicia A. McDonough. Renal NHE3 and NaPi2 partition into distinct membrane domains. Am J Physiol Cell Physiol, Apr 2009; 296: C900 – C910.
- Donna H. Lee, Anne D. M. Riquier, Li E. Yang, Patrick K. K. Leong, Arvid B. Maunsbach, and Alicia A. McDonough. Acute hypertension provokes acute trafficking of distal tubule NaCl co-transporter (NCC) to subapical cytoplasmic vesicles. Am J Physiol Renal Physiol, Apr 2009; 296: F810-F818.
- Monica B. Sandberg, Anne D. M. Riquier, Kaarina Pihakaski-Maunsbach, Alicia A. McDonough, and Arvid B. Maunsbach. Angiotensin II provokes acute trafficking of distal tubule NaCl co-transporter (NCC) to apical membrane. Am J Physiol Renal Physiol, Sep 2007; 293: F662 – F669.