Protein Could Prevent Kidney Failure in Alport Syndrome

Scientists from Japan’s Kumamoto University have discovered a protein that puts the brakes on the progression of Alport syndrome, a rare genetic kidney disease that can affect children and young people and often leads to kidney failure. The protein, known as p53, is a tumor suppressor, already targeted by experimental cancer…

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Amniotic Fluid Stem Cells Slow Kidney Disease Progression

Scientists at the Saban Research Institute at The Children’s Hospital Los Angeles have shown that stem cells from amniotic fluid can slow kidney disease progression in mice with Alport syndrome. Treating the mice with stem cells prior to the onset of proteinuria improved survival rates, delayed the progression of kidney…

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Kidney Stem Cell Breakthrough Provides Tool for Further Research

Australian researchers have discovered how to turn specialized human kidney cells back into generalized cells known as induced pluripotent stem cells or iPS cells. This type of cell reprogramming is a useful tool for studying genetic kidney diseases.  The scientists hope to generate iPS cells from patients with Polycystic Kidney…

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