Anti-Aging Hormone Klotho Inhibits Kidney Damage


Scientists at UT Southwestern Medical Center have discovered that the anti-aging hormone Klotho inhibits renal fibrosis by blocking signaling pathways that can cause tissue damage. Klotho works in a similar way to stop the spread of cancer.  In addition to its potential uses in the treatment of chronic kidney disease and acute kidney injury, Klotho … Continue reading Anti-Aging Hormone Klotho Inhibits Kidney Damage

Low Levels of Hormone Klotho May Be Early Warning Sign of CKD


Researchers from UT Southwestern Medical Center have discovered that Klotho, an anti-aging hormone produced in the kidneys, may serve as a biomarker for early CKD and its cardiovascular complications.  Low levels of Klotho have been observed in both mice and humans with CKD. The senior author of the study, Dr. Orson Moe said, “It can … Continue reading Low Levels of Hormone Klotho May Be Early Warning Sign of CKD