Neo-Kidney Augment Phase 1 Trials Under Way

Phase 1 trials of the Neo-Kidney Augment, a novel, personalized treatment designed to enhance or replace kidney function in patients nearing renal failure, are under way in Sweden and the United States. Developed by regenerative medicine company Tengion, the Neo-Kidney Augment uses tubular epithelial cells taken from a biopsy of…

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Milestone Reached in Work to Build Replacement Kidneys in the Lab

Researchers at Wake Forest Baptist Medical Center are advancing the field of regenerative medicine with a new method to keep blood vessels open and viable in lab-built kidneys. Experimenting with scaffolds created from pig kidneys, the scientists coated the scaffold vessels with endothelial cells, using an antibody to facilitate cell…

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Exciting Research Partnerships at USC May Unlock Cures for Kidney Disease

Exciting research partnerships at USC may unlock new treatments and cures for kidney disease. A recent USC article highlights the promising stem cell work of Andrew McMahon, Ph.D., director of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, leader of the USC Stem…

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Cellular Signaling Responsible for Kidney Regeneration Discovered

With their exciting discovery of the cellular signaling responsible for renal regeneration, scientists from Sheba Medical Center, Tel Aviv University, and Stanford University aim to change the way researchers think about kidneys. Using a special mouse model to track cell growth in vivo, they made surprising discoveries about how growth…

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Gene Linked to Pediatric Kidney Cancer May Be Key to Kidney Regeneration

Researchers from Boston Children’s Hospital have made several important discoveries about the gene Lin28 and its link to Wilms tumor, a pediatric renal cancer marked by growths that appear similar to immature kidneys. Experts believe the tumors are caused by unchecked kidney development, which would normally be complete before birth.…

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Scientists Bioengineer Functioning Rat Kidneys

Researchers from Massachusetts General Hospital have succeeded in growing bioengineered kidneys in the lab and implanting them into rats. To create the functioning organs, they began by using a detergent solution to strip rat kidneys of their existing cells. This resulted in a collagen scaffold, where a variety of cell…

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