Citrus Fruit Compound Naringenin Could Prevent PKD Cysts


A team of scientists in England has found that naringenin, an antioxidant and anti-inflammatory compound in grapefruit, oranges and tomatoes, could be the basis for a promising new treatment for polycystic kidney disease (PKD). Using a single-celled amoeba, they found that naringenin inhibits PKD cysts by regulating levels of the PKD2 protein (also known as … Continue reading Citrus Fruit Compound Naringenin Could Prevent PKD Cysts

Surprising Mechanism Discovered in PKD


Researchers from Yale University School of Medicine have discovered a new mechanism that affects both the severity and progression of PKD. Previously, cyst growth has been linked to mutations in the PKD1 and PKD2 genes and their associated proteins, polycystin-1 and -2. Scientists have found that defective cilia in renal tube cells also play a … Continue reading Surprising Mechanism Discovered in PKD