Mutations in Gene Essential for Cell Regulation Cause Kidney Cancer in Kids

Scientists from The Institute of Cancer Research in London have discovered that mutations in the CTR9 gene are responsible for Wilms tumor in some children with an inherited form of the kidney cancer. CTR9 is a component of the PAF1 protein complex, which plays a part in telling genes to…

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Gene Linked to Pediatric Kidney Cancer May Be Key to Kidney Regeneration

Researchers from Boston Children’s Hospital have made several important discoveries about the gene Lin28 and its link to Wilms tumor, a pediatric renal cancer marked by growths that appear similar to immature kidneys. Experts believe the tumors are caused by unchecked kidney development, which would normally be complete before birth.…

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Genetic Mutations Linked to Childhood Kidney Cancer, Wilms Tumor

A team of international researchers led by the Institute of Cancer Research in the UK have found two regions of the human genome linked to increased risk for the most common form of childhood kidney cancer, Wilms tumor. Scientists have suspected a genetic role in the rare disease because it…

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