Guest Post by Janos Peti-Peterdi, M.D., Ph.D. and Georgina Gyarmati, M.D., Ph.D. Our research team is driven by a personal and professional mission to find a cure for kidney disease, a growing global epidemic affecting one out of seven adults, which translates to 850 million people worldwide or about two million in the Los Angeles … Continue reading Kidney Regeneration Breakthrough at Keck School of Medicine of USC
Researchers Isolate Human Kidney Progenitor Cells
Scientists from the Saban Research Institute of Children’s Hospital Los Angeles have made an exciting discovery, isolating human kidney progenitor cells without genetic manipulation using a novel in vivo technique. These nephrogenic progenitor cells (NPs) give rise to mature nephrons, the key filtering units in the kidney. Although scientists have studied NPs in mice, this breakthrough in … Continue reading Researchers Isolate Human Kidney Progenitor Cells
Gli1 Stem Cells Could Stop Major Killer of Kidney Patients
A team of researchers led by investigators from Washington University School of Medicine in St. Louis has identified the stem cells responsible for calcium buildup in the arteries, a major problem for kidney disease patients. Found in the outer layers of the arteries, Gli1 positive stem cells have the ability to change cell type depending on … Continue reading Gli1 Stem Cells Could Stop Major Killer of Kidney Patients
Stem Cells That Form Kidney Blood Vessels Identified
An exciting stem cell discovery from researchers at University of Virginia Medical School brings scientists one step closer to growing kidneys in the lab, complete with functioning vasculature. The UVA investigators not only identified the stem cells that produce blood vessels in the kidney, they also found that blood forms along with the vessels. Their … Continue reading Stem Cells That Form Kidney Blood Vessels Identified
Mini Kidneys Grown In Lab Mimic Disease
Using stem cell and gene-editing techniques, researchers from Brigham and Women’s Hospital have succeeded in growing mini kidneys that mimic disease. These tiny, impressive organoids, just 1 mm in diameter, are capable of modeling healthy as well as diseased kidneys and contain kidney tubules resembling those in people. They can also survive after transplantation in … Continue reading Mini Kidneys Grown In Lab Mimic Disease
Stem Cell Therapy Points to Acute Kidney Injury Treatment
Researchers from Kyoto University in Japan have employed a novel stem cell therapy that could lead to a treatment for acute kidney injury (AKI). Working with a mouse model of AKI, the scientists administered renal progenitor cells—early, short-lived kidney cells—created from human induced pluripotent stem cells. Interestingly, the transplanted progenitor cells did not need to … Continue reading Stem Cell Therapy Points to Acute Kidney Injury Treatment