A Stem Cell Revolution

Scientists at the USC/UKRO Kidney Research Center and a wide-reaching team of collaborators are pioneering a cure – a transplantable synthetic kidney – bringing hope to the 100,000+ Americans that are currently on the transplant list.

It all begins with cells nurtured in a Petri dish, eventually growing into a full-fledged kidney through advanced bioengineering.

In just 10 years, we anticipate these synthetic kidneys will be undergoing FDA trials and making their debut in human treatments.

Today, stem cell-derived mini cystic kidneys are already being used to model polycystic kidney disease (PKD) and perform drug screening to identify novel therapies.

Andrew McMahon and Zhongwei Li

Meet our visionary researchers, Dr. Andrew McMahon, Director of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, and Dr. Zhongwei Li, Assistant Professor of Medicine and Stem Cell Biology and Regenerative Medicine. Dr. Li’s groundbreaking work has recently been recognized with a prestigious grant from the National Institutes of Health (NIH). His mastery of stem cells and Dr. McMahon’s expertise in kidney development bring us closer to rewriting the history of kidney disease.

Your donation will accelerate this life-saving research.