UCSB Researchers Discover Drug Target for PKD


Researchers at UC Santa Barbara have discovered that the same molecular mechanism that causes cancer cells to multiply also causes cysts to grow in patients with ADPKD, the most common form of Polycystic Kidney Disease. They found that the transcription factor STAT3 is activated by a mutated protein present in ADPKD patients. UCSB researchers are … Continue reading UCSB Researchers Discover Drug Target for PKD

Scientists Discover Role of PVT1 Gene in Diabetic Kidney Disease


Researchers at the Translational Genomics Research Institute (TGen) in Phoenix, Arizona are shedding new light on the role of the PVT1 gene in reducing kidney filtration and causing diabetic kidney disease. They discovered that high blood sugar increases the rate of PVT1 gene expression, unleashing proteins associated with damage to the mesangial cells of the … Continue reading Scientists Discover Role of PVT1 Gene in Diabetic Kidney Disease

Research Breakthrough – Kidneys Grown in Lab in Scotland


Scottish researchers at the University of Edinburgh have managed to grow tiny kidneys measuring just 0.2 inches long. Their breakthrough represents a giant leap forward in the future treatment of kidney disease. The organs, created in the lab using stem cells from human amniotic fluid and animal fetal cells, are of the same size and … Continue reading Research Breakthrough – Kidneys Grown in Lab in Scotland

Low Levels of Hormone Klotho May Be Early Warning Sign of CKD


Researchers from UT Southwestern Medical Center have discovered that Klotho, an anti-aging hormone produced in the kidneys, may serve as a biomarker for early CKD and its cardiovascular complications.  Low levels of Klotho have been observed in both mice and humans with CKD. The senior author of the study, Dr. Orson Moe said, “It can … Continue reading Low Levels of Hormone Klotho May Be Early Warning Sign of CKD