UKRO – University Kidney Research Organization
Together We Build a Kidney
Mount Sinai School of Medicine researchers have found that a special diet high in fat and low in carbohydrates, known as the ketogenic diet, can reverse kidney damage in mice with Type 1 and Type 2 diabetes. The 8-week diet completely reversed albuminuria and partially reversed glomerular sclerosis. During the study, the research team discovered … Continue reading High Fat, Low Carb Diet Improves Kidney Disease in Diabetic Mice
Researchers at University of Miami Miller School of Medicine, collaborating with a team of doctors and surgeons, have uncovered how the drug Rituximab, normally used to treat non-Hodgkin’s lymphoma, rheumatoid arthritis, and chronic lymphocytic leukemia, also works to prevent FSGS from recurring in children and young adults with kidney transplants. The drug appears to bind … Continue reading Cancer Drug May Help Stop Recurring FSGS in Kidney Transplant Patients
Scientists at UT Southwestern Medical Center have discovered that the anti-aging hormone Klotho inhibits renal fibrosis by blocking signaling pathways that can cause tissue damage. Klotho works in a similar way to stop the spread of cancer. In addition to its potential uses in the treatment of chronic kidney disease and acute kidney injury, Klotho … Continue reading Anti-Aging Hormone Klotho Inhibits Kidney Damage
Researchers from the United States, Italy, and China have joined together to unravel the mysteries of IgA nephropathy, a disease that is the leading cause of kidney failure in Asia and Southern Europe. Scientists studying a group of IgA nephropathy patients of Chinese and European heritage uncovered five regions of the human genome associated with … Continue reading Researchers Find Genetic Clues to IgA Nephropathy
Researchers at Wake Forest Baptist Medical Center have discovered that variations in a gene called APOL1 explain why transplanted kidneys from some African American donors don’t last as long as others. The study showed that 2 copies of the recessive gene hindered kidney survival. The genetic anomaly, affecting 10 to 12 percent of African Americans, … Continue reading Gene Impacts Donor Kidney Survival, Could Increase CKD Risk
Some interesting kidney-related research stories came out of last week’s American Urological Association Meeting in Washington, D.C. Researchers have found that what’s good for the heart is also good for preventing kidney stones. And they believe that kidney stones may be an indicator of possible heart disease. – What Protects the Heart May Also Protect … Continue reading Kidney Research Highlights from American Urological Assoc. Meeting