Researchers from Cleveland Clinic have discovered an important connection between the gut bacteria byproduct, TMAO, and chronic kidney disease. TMAO (trimethylamine N-oxide) is produced when we digest choline and carnitine, found in animal sources—dairy, egg yolks, red meat, and liver. The researchers studied subjects with and without chronic kidney disease and found a link between … Continue reading Gut Bacteria Byproduct Linked to Chronic Kidney Disease
Vascular Calcification May Explain Link Between Kidney Stones and Heart Disease
New research suggests that blood vessel calcification may explain the link between kidney stones and heart disease. Vascular calcification is common in chronic kidney disease patients and puts them at high risk of cardiovascular death. Researchers led by Linda Shavit, M.D. of University College London Medical School and Israel’s Shaare Zedek Medical Center, used CT … Continue reading Vascular Calcification May Explain Link Between Kidney Stones and Heart Disease
Biomarkers Linked to Long-Term Kidney Damage, Death in AKI Patients
An international research team led by University of Pittsburgh School of Medicine has linked high levels of TIMP2 and IGFBP7, two biomarkers for acute kidney injury (AKI), to long-term kidney damage, the risk of needing dialysis or a transplant, and death in patients in the early stages of the disease. The discovery could help physicians identify … Continue reading Biomarkers Linked to Long-Term Kidney Damage, Death in AKI Patients
Dr. Janos Peti-Peterdi Recommended for American Society for Clinical Investigation Membership
We are happy to announce that Janos Peti-Peterdi, M.D., Ph.D., Professor of Physiology and Biophysics, and Medicine at the Zilkha Neurogenetic Institute at the Keck School of Medicine of the University of Southern California has been recommended for membership by the council of the American Society for Clinical Investigation for his pioneering research on kidney … Continue reading Dr. Janos Peti-Peterdi Recommended for American Society for Clinical Investigation Membership
Defective Energy Production in Kidney Cells Key to Fibrosis and CKD
A team of researchers led by scientists from Perelman School of Medicine at University of Pennsylvania has found that defective fatty acid metabolism in kidney tubular epithelial cells plays a key role in the development of fibrosis and chronic kidney disease. Genetic analysis of healthy and fibrotic human kidney tissue led to their discovery of … Continue reading Defective Energy Production in Kidney Cells Key to Fibrosis and CKD
Researchers Tame the Inflammatory Response in Kidney Dialysis
Researchers from Perelman School of Medicine at University of Pennyslvania have found a way to temporarily suppress the damaging inflammatory response brought on by dialysis. In earlier studies, the research team showed that polymer-based dialysis filters activate the body’s complement system, a part of the immune system made up of circulating proteins that help antibodies … Continue reading Researchers Tame the Inflammatory Response in Kidney Dialysis