Researchers at Wake Forest Baptist Medical Center are advancing the field of regenerative medicine with a new method to keep blood vessels open and viable in lab-built kidneys. Experimenting with scaffolds created from pig kidneys, the scientists coated the scaffold vessels with endothelial cells, using an antibody to facilitate cell adhesion. The treated vessels supported … Continue reading Milestone Reached in Work to Build Replacement Kidneys in the Lab
USC Researchers Honored For Work on Hypertension and Novel Imaging of Podocytes
We are happy to announce that USC researchers and members of UKRO’s Medical Scientific Advisory Board, Alicia McDonough, Ph.D. and Janos Peti-Peterdi, M.D., Ph.D. were recently honored for their exciting investigative work. Earlier this month, Dr. McDonough delivered the Seldin Award Lecture on “Intrarenal Mechanisms Controlling Potassium and Blood Pressure Homeostasis.” The Seldin Award Lecture … Continue reading USC Researchers Honored For Work on Hypertension and Novel Imaging of Podocytes
Top News on Uric Acid and Gout
Gout was once thought of as a disease only for kings or the wealthy, brought on by overindulgence in rich foods, read meat, and alcohol, but today this painful condition is more prevalent in the general population than you might think. A form of arthritis, gout occurs when uric acid builds up in the blood, … Continue reading Top News on Uric Acid and Gout
Mutations in Gene Essential for Cell Regulation Cause Kidney Cancer in Kids
Scientists from The Institute of Cancer Research in London have discovered that mutations in the CTR9 gene are responsible for Wilms tumor in some children with an inherited form of the kidney cancer. CTR9 is a component of the PAF1 protein complex, which plays a part in telling genes to shut on or off. The … Continue reading Mutations in Gene Essential for Cell Regulation Cause Kidney Cancer in Kids
Stem Cell Scientists Lay TRAP for Kidney Disease
Scientists from Dr. Andrew McMahon’s stem cell lab at USC have uncovered the cellular responses that occur within damaged kidneys by using a unique “TRAP” mouse model. Their research builds upon TRAP (translating ribosome affinity purification), a method used to tag ribosomes, molecular structures that contain RNA and are responsible for protein synthesis. The scientists … Continue reading Stem Cell Scientists Lay TRAP for Kidney Disease
Exciting Research Partnerships at USC May Unlock Cures for Kidney Disease
Exciting research partnerships at USC may unlock new treatments and cures for kidney disease. A recent USC article highlights the promising stem cell work of Andrew McMahon, Ph.D., director of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, leader of the USC Stem Cell Initiative, and member of … Continue reading Exciting Research Partnerships at USC May Unlock Cures for Kidney Disease