Researchers from Indiana University School of Medicine have shown that renal stem cell transplants may have the potential to repair damaged kidneys. In the study using rats with acute kidney injury and CKD, the scientists reprogrammed adult kidney cells to express the SAA gene, thus producing the SAA protein, which is essential to early kidney … Continue reading Kidney Cell Transplants May One Day Be Used to Treat Renal Failure
Renal Denervation Lowers Blood Pressure for Patients with Moderate to Severe CKD
A team of researchers from Baker IDI Heart and Diabetes Institute in Australia have shown that renal denervation, a new investigational technique to curb hard-to-treat blood pressure is safe in the short term for hypertensive patients with stage 3 to 4 CKD. Renal denervation uses radio frequency waves to deaden certain overactive sympathetic nerves in … Continue reading Renal Denervation Lowers Blood Pressure for Patients with Moderate to Severe CKD
New Equation to Predict Risk of Death & ESRD for Patients with Impaired Kidney Function
In a study comparing equations that assess glomerular filtration rate and the risk of mortality and ESRD, a team of researchers have found that a newer equation, CKD-EPI, may prove more beneficial than the current standard, MDRD. Data from 1.1 million adults from 40 countries showed that CKD-EPI more accurately predicted risk of death and … Continue reading New Equation to Predict Risk of Death & ESRD for Patients with Impaired Kidney Function
ACE2 Molecule May Protect Against Diabetic Complications Including Kidney Damage
A team of researchers from University of Alberta and University of Florida have shown that angiotensin-converting enzyme-2 or ACE2 can protect against diabetic complications, specifically heart damage, in diabetic mice. Their previous research demonstrated that ACE2 protects the kidneys as well. ACE2 protects by breaking down Angiotensin II, a hormone which contributes to high blood … Continue reading ACE2 Molecule May Protect Against Diabetic Complications Including Kidney Damage
Genetic Mutations Linked to Childhood Kidney Cancer, Wilms Tumor
A team of international researchers led by the Institute of Cancer Research in the UK have found two regions of the human genome linked to increased risk for the most common form of childhood kidney cancer, Wilms tumor. Scientists have suspected a genetic role in the rare disease because it can occur in siblings and … Continue reading Genetic Mutations Linked to Childhood Kidney Cancer, Wilms Tumor
Researchers Use Normothermic Perfusion to Increase Success of Kidney Transplants
Scientists from Kidney Research UK have discovered a way to increase the success of kidney transplants from deceased donors by reviving the kidneys prior to transplantation using normothermic perfusion. Blood flow is reintroduced to the kidney via a special machine, effectively reversing the damage caused by storing the kidney on ice. The scientists believe kidneys … Continue reading Researchers Use Normothermic Perfusion to Increase Success of Kidney Transplants