Poor Kidney Function Linked to Brain Disorders

A 2,645 person, population-based study conducted by researchers from Erasmus University Medical Center in the Netherlands highlights a link between poor kidney function and brain disorders. The scientists uncovered an intriguing association between poor kidney function and decreased blood supply to the brain. They also found that those participants with…

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Study Uncovers Gene That Causes Kidney Cells to Self-Destruct

Researchers from the Icahn School of Medicine at Mount Sinai have uncovered a gene that could prove to be a promising target to stop the progression of kidney disease. Using a mouse model, the scientists identified genes that are overexpressed as kidney disease worsens, hitting upon the RTN1 gene as…

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Janos Peti-Peterdi Wins Young Investigator Award

We congratulate USC researcher and UKRO Medical Scientific Advisory Board Member, Janos Peti-Peterdi, M.D., Ph.D., on winning the Young Investigator Award for his outstanding achievement and creativity in kidney research. Co-sponsored by the American Society of Nephrology and the American Heart Association Council on the Kidney, the honor includes a…

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NSAIDs May Increase Kidney Disease Risk for Hypertensive Patients

A study from Taiwan warns that common pain medications known as NSAIDs may increase the risk of kidney disease in those with high blood pressure. NSAIDs or non-steroidal anti-inflammatory drugs include aspirin, ibuprofen (Motrin, Advil), and naproxen (Aleve). High blood pressure is already a risk factor for kidney disease. The…

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Stem Cell Therapy Points to Acute Kidney Injury Treatment

Researchers from Kyoto University in Japan have employed a novel stem cell therapy that could lead to a treatment for acute kidney injury (AKI). Working with a mouse model of AKI, the scientists administered renal progenitor cells—early, short-lived kidney cells—created from human induced pluripotent stem cells. Interestingly, the transplanted progenitor…

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Age-Related Cellular Signal Puts Kidneys at Risk

Scientists from the University of Missouri have identified a cellular signal that makes aging kidneys vulnerable to injury. They found that low levels of a protein called alpha (E) catenin can occur with age, triggering first an increase in kidney cells, then the mass death of healthy cells in a…

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