Zinc Levels May Contribute to Kidney Stones

A team of researchers led by scientists from UC San Francisco has discovered that zinc levels play a part in kidney stone formation and could represent a promising therapeutic target. Working with a fruit fly model as well as humans, they examined the relationship between zinc and the minerals that…

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Study Shows How Kidneys Protect Themselves from Inflammation

Researchers at the Medical College of Georgia at Georgia Regents University have discovered how the kidneys protect themselves from damaging inflammation. In mouse studies, they found that kidney podocyte cells produce the enzyme IDO in response to inflammation. Human kidney patients also exhibit high levels of the enzyme. Blocking IDO…

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New PKD Treatment Targets Kidney Blood Vessels

Researchers from the University of Manchester and University College London believe targeting the small blood vessels surrounding renal cysts could lead to a new treatment for polycystic kidney disease. They uncovered important abnormalities in the network of these blood vessels in mouse models of the most common form of PKD…

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Research Breakthrough in Fight Against Membranous Nephropathy

University of Manchester researchers have made a major breakthrough that could lead to two new treatments for membranous nephropathy or MN, a rare kidney disease in which the immune system attacks a protein found in the kidneys, causing thickening of the small blood vessels in the kidney, proteinuria, and sometimes…

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Scientists Discover How Renalase Protects Kidneys, Heart

Yale School of Medicine researchers have uncovered how renalase, a protein produced by the kidneys, protects the cells of the kidneys and heart from injury. In 2005, Yale researchers discovered and named the protein, which regulates heart rate and blood pressure. Early research showed that patients with kidney disease had…

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Stem Cells and Anti-Scarring Protein May Help Heal Kidneys

A research team led by scientists from Monash University in Australia may have found the right combination to heal injured kidneys—adult stem cells and an anti-fibrotic protein called serelaxin. Neither therapy works as well when administered independently. Serelaxin appears to pave the way for healing by reducing scarring, creating conditions…

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