Computer Modeling Points to New Drug Target for PKD

Researchers from Indiana University have made important discoveries about PKD cyst formation using virtual tissue technology. Building a virtual nephron, the scientists used computer simulation to show that PKD gene mutations caused errors in cell adhesion. When cells failed to stick together, they formed mushroom-shaped cysts. When cells stuck together,…

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Inflammation Linked to Diabetes After Transplant

Researchers have been unable to explain why up to 30 percent of organ transplant patients develop diabetes. Immunosuppressant drugs have topped the list of possible causes, leading doctors to believe that diabetes may be inevitable for some patients. A new study from Thomas Jefferson University in Pennsylvania reveals that the…

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Smoking Poses Kidney Risk for African Americans

While the link between smoking and kidney disease risk is well known, a new study from the University of Mississippi Medical Center shows that smoking may be particularly harmful for African Americans. The researchers were able to analyze kidney function and decline in 3,648 African Americans ranging in age from 21 to 84…

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Gut Bacteria Linked to Poor Health in Kidney Disease Patients

Scientists are only just beginning to learn the many ways our gut microbiota can contribute to both good health and disease. A research team from Belgium’s University Hospitals Leuven has uncovered a link between high levels of a gut bacterial metabolite called PAG (phenylacetylglutamine) and poor health in patients with…

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Top News on Kidney Transplant Innovations

Our roundup of the latest kidney transplant news brings together exciting studies and innovations designed to increase successful transplants by improving the procurement system, introducing new procedures, and maximizing the use of donor organs. A recent article in the New York Times describes a promising new transplant procedure called desensitization, which…

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Do Female Hormones Protect the Kidney?

Two new studies point to interesting evidence that female hormones may protect women’s kidneys from damage, suggesting novel gender-based avenues to safeguard kidney health for women and men. Research from the Perelman School of Medicine at the University of Pennsylvania suggests that female hormones may provide greater resistance to kidney damage following a kidney transplant.…

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